DIM (3,3'-diindolylmethane)

Diindolylmethane is derived from cruciferous vegetables as the primary metabolite of the compound Indole 3 Carbinol [I3C] found in brussel sprouts, cabbage, cauliflower, cabbage, and other members of the cruciferous vegetable group. These vegetables are thought to have cellular protective effects on a variety of pathways. I3C is converted to DIM by a plant derived enzyme called myrosinase. Myrosinase is also produced by some but not all people in their gut flora. DIM is thought to have a number of positive metabolic effects on differing body systems. It may limit the accumulation of body fat. It has been shown to have immunomodulating effects. It also has antioxidant properties and may protect cells from radiation damage. Diets that include significant amounts of cruciferous vegetables have shown numerous health benefits. A number of these benefits are believed to be due to I3C and its active metabolite DIM. [1,2,3,4,5].